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What can be expected from the cytologic examination of cervicovaginal smears for the diagnosis of Chlamydia trachomatis infections?

Source

Laboratories of Histology, Faculty of Medicine, Louis Pasteur University, Strasbourg, France.et helas de la faculte de medecine de constantine

Abstract

The value of Papanicolaou-stained smears for the diagnosis of chlamydial infections is still disputed. A comparative examination of smears from infected and uninfected women has allowed the proposal of a new scheme for the interpretation of the cytologic abnormalities associated with chlamydial infection. In particular, the appearances of metaplastic cells were classified, and two smear types were found to have the highest sensitivities and positive predictive values: smears in which the metaplastic cells had (1) intracytoplasmic vacuoles containing polymorphonuclear leukocytes or (2) numerous small intracytoplasmic vacuoles containing a central eosinophilic granule. The sensitivity of this method is low, however; cytology cannot replace bacteriologic identification for the diagnosis of chlamydial infections. Nevertheless, the examination of Papanicolaou-stained smears could be considered as a screening tool in low-risk populations; provided that all of the cytologic features were considered, presumptive diagnoses of chlamydial infections could be obtained.

PMID:
3201874
[PubMed - indexed for MEDLINE]

LinkOut - more resources

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    de C Ghirardini - 1991 - Cité 1 fois - Autres articles
    detection of Chlamydia trachomatis and its possible relevant role ..... Sekhri A, Le Faou AE, Tardieu J-C, Antz M, Fabre M. What can ...
    onlinelibrary.wiley.com/doi/10.1002/dc.2840070221/pdf
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    de CM Bates - 1993 - Cité 2 fois - Autres articles
    Sixty eight per cent were able to test for Chlamydia trachomatis. ... [PubMed]; Sekhri A, Le Faou AE, Tardieu JC, Antz M, Fabre M. What can be expected from ...
    www.ncbi.nlm.nih.gov/pmc/articles/PMC1195045/
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    Format de fichier: PDF/Adobe Acrobat - Afficher
    de A McMillan - 2006 - Cité 4 fois - Autres articles
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    de GÜR Vural - 1995 - Cité 4 fois - Autres articles
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    Chlamydia trachomatis is an obligate intracellular bacterium that infects ..... Sekhri A, LeFaou AE, Tardieu JC, Antz M, Fabre M. What can be expected from ...
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      Format de fichier: PDF/Adobe Acrobat - Afficher
      de CM Bates - 1993 - Cité 2 fois - Autres articles
      city in respect of Chlamydia trachomatis is dis- puted.'3. As a result of the British Society for ..... 4 Sekhri A, Le Faou AE, Tardieu JC, Antz M, Fabre M. ...
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    3. The detection of genital tract infection by Papanicolaou-stained ...

      de A McMillan - 2006 - Cité 4 fois - Autres articles
      27 Nov 2006 – Genital tract infection with Chlamydia trachomatis is common, ..... Sekhri A, Le Faou AE, Tardieu JC, Antz M, Fabre M. What can be expected ...
      onlinelibrary.wiley.com/doi/10.1111/j.1365-2303.2006.00411.x/full



02/07/2011
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